2014 Program

April 10, 2014

2:00pm - 2:10pm Welcome Remarks
Brian Herman, Ph.D.
Vice President of Research, University of Minnesota
2:10pm - 2:50pm Plenary Talk: Adjusting Malfunctioning Brain Circuits with Deep Brain Stimulation
Andres Lozano, M.D., Ph.D.
RR Tasker Professor and Chairman of Neurosurgery, University of Toronto
Moderator: Bin He (University of Minnesota)
2:50pm - 3:10pm Technology Considerations for Enabling Bi-directional Neural Interfaces
Tim Denison, Ph.D.
Technical Fellow and Director of Core Technology, Medtronic Neuromodulation
Moderator: Matthew Johnson (University of Minnesota)
3:10pm - 3:30pm Technical Considerations for Advanced Stimulation Control
Rafael Carbunaru, Ph.D.
Vice President, Research & Development, Boston Scientific Neuromodulation
Moderator: Hubert Lim (University of Minnesota)
3:30pm - 3:50pm FDA and Medical Devices
Anindita Saha
Acting Director, External Expertise and Partnerships, FDA/CDRH/OCD
Moderator: Hubert Lim (University of Minnesota)
3:50pm - 4:10pm Coffee Break
4:10pm - 4:50pm Panel Discussion: Challenges and Trends in DBS
Panelists: R. Carbunaru, T. Denison, K. Lee, A. Lozano, H. Mayberg, G. Molnar, A. Saha
4:50pm - 5:10pm Neuromodulation and the NIH
Kip Ludwig, Ph.D.
Program Director of Neural Engineering, National Institutes of Health, NINDS
Moderator: Bin He (University of Minnesota)
5:10pm - 5:30pm RENET Program and Future Directions of Neural Interface Portfolio
Douglas Weber, Ph.D.
Program Manager, DARPA Microsystems Technology Office
Moderator: Bin He (University of Minnesota)
5:30pm - 5:50pm Panel Discussion: Federal Funding
Panelists: Kip Ludwig and Douglas Weber
5:50pm - 7:30pm Reception

April 11, 2014

8:30am - 9:10am Plenary Talk: Optimizing DBS for Depression
Helen S. Mayberg, M.D.
Professor, Psychiatry, Neurology and Radiology and Dorothy C. Fuqua Chair in Psychiatric Neuroimaging and Therapeutics, Emory University School of Medicine Moderator: Timothy Ebner (University of Minnesota)
9:10am - 9:30am Combining Electrochemical Detection and fMRI to Elucidate Mechanism of Action of DBS
P. Hunter Peckham, PhD
Donnell Institute Professor of Biomedical Engineering
Case Western Reserve University
Member, National Academy of Engineering
Moderator: Matthew Johnson (UMN)
9:30am - 9:50am Low Frequency Neuromodulation for Seizure Control
Dominique M. Durand, Ph.D.
Linsedth Professor of Biomedical Engineering and Director of Neural Engineering Center, Case Western Reserve University
Moderator: John Troy (Northwestern University)
9:50am - 10:10am Coffee Break
10:10am - 12:00pm Poster Session
12:00pm - 13:00pm Career Panel for Students and Postdocs
Panelists: Kip Ludwig, G. Molnar, R. Nelson, D. Smith
Moderator: Tay Netoff (University of Minnesota)
1:10pm - 1:50pm Plenary Talk: History and Principles of Transcranial Magnetic Stimulation
Anthony T. Barker, Ph.D.
Consultant Clinical Scientist, Royal Hallamshire Hospital, U.K.
Kyushu University, Japan
Moderator: Kelvin Lim (University of Minnesota)
1:50pm - 2:10pm Technology and Mechanisms of Transcranial Direct Current Stimulation
Marom Bikson, Ph.D.
Associate Professor of Biomedical Engineering
The City College of The City University of New York
Moderator: Wei Chen (University of Minnesota)
2:10pm - 2:40pm Panel Discussion: Noninvasive Neuromodulation
Panelists: Drs. A. T. Barker, M. Bikson , J. Carey
2:40pm - 3:00pm Closing Ceremony – Announcement of Poster Awards

Best Poster Awards

1ST PLACE:

Motor Behavior of the Human Lumbar Spinal Cord Network Responding to Externally Controlled Activity: A Neurophysiological Study
Simon M. Danner, Milan R. Dimitrijevic, Ursula S. Hofstoetter, Matthias Krenn, Winfried Mayr, Karen Minassian, Frank Rattay and John C. Rothwell
Vienna University of Technology, Austria

Deep Brain Stimulation of the Inferior Colliculus for Treating Tinnitus
Sarah J. Offutt, Alexander R. Konop, Hubert H. Lim
University of Minnesota, Minneapolis, MN

2ND PLACE:

Direct Measurement of the Response of PFC Pyramidal Neurons to Magnetic Stimulation
Seung Woo Lee, Shelley I. Fried
Harvard Medical School/MGH, Boston, MA

High Definition Transcranial Direct Current Stimulation Acutely Modulates Spontaneous Low Frequency Cortical Synchronization: Evidence from Simultaneous tDCS-EEG
Abhrajeet Roy, Bryan Baxter, Bin He
University of Minnesota, Minneapolis, MN

Utilizing Individual Endogenous Synchrony Dynamics in the Design of Electrical Deep Brain Stimulation Improves the Efficacy of Disrupting Temporal Lobe Seizures
Tiwalade Sobayo, David J. Mogul
Illinois Institute of Technology, Chicago, IL

3RD PLACE:

Effect of rTMS and Sensorimotor Retraining in Focal Dystonia
Rebekah L. Schmidt, Mo Chen, Catherin M. Buetefisch, Teresa J. Kimberley
University of Minnesota, Minneapolis, MN

 

Poster Presentations

 

INVASIVE NEUROMODULATION 

Spatial and Frequency-Dependent Effects of VPLo-Thalamus Stimulation on Motor Cortex Activity
Filippo Agnesi, Allison T. Connolly, Joe Xiao, Matthew D. Johnson
University of Minnesota, Minneapolis, MN

Diamond-Based Electrodes for Fast-Scan Cyclic Voltammetry 1: Electrode Engineering and Fabrication
Kevin E. Bennet, Jonathan R. Tomshine, Felicia Manciu, Mike Marsh, Kendall Lee
Mayo Clinic, Rochester, MN

Diamond-Based Electrodes for Fast-Scan Cyclic Voltammetry 2: In Vivo Application
Jonathan R. Tomshine, Kevin E. Bennet, Inyong Kim, Kendall Lee
Mayo Clinic, Rochester, MN

Targeted Deep Brain Stimulation of the Central Thalamus Augments Behaviors and Arousal
Jonathan L. Baker, Xuefeng F. Wei, Jae-Wook Ryou, Christopher R. Butson, Nicholas D. Schiff, Keith P. Purpura
Weill Cornell Medical College, New York, NY

Current Steering Validation Using a Radially-Segmented Deep Brain Stimulation Array
Allison T. Connolly, Benjamin A. Teplitzky, Matthew D. Johnson
University of Minnesota, Minneapolis, MN

Motor Behavior of the Human Lumbar Spinal Cord Network Responding to Externally Controlled Activity: A Neurophysiological Study
Simon M. Danner, Milan R. Dimitrijevic, Ursula S. Hofstoetter, Matthias Krenn, Winfried Mayr, Karen Minassian, Frank Rattay and John C. Rothwell
Vienna University of Technology, Austria

Investigating the Network Effect of STN DBS in Humans with 1.5T fMRI
William S. Gibson, Hoon-Ki Min, Emily J. Knight, Joel P. Felmlee, Krzysztof R. Gorny, Bryan T. Klassen, SuYoune Chang, Kendall H. Lee
Mayo Clinic, Rochester, MN

Intraspinal Microstimulation Using MINCS to Evoke Hind Limb Movements in a Porcine Model of Spinal Stimulation
Peter Grahn, Grant Mallory, B. Michael Berry, Obaid Khurram, Juho Jeong, Allen Bieber, Kendall Lee, Luis Lujan
Mayo Clinic, Rochester, MN

The development of a closed loop controller for deep brain stimulation in porcine model: toward smart neuromodulation
Grant W. Mallory, B. Michael Berry, Inyong Kim, Seungleal Paek, Peter J. Grahn, Obaid Khurram, Allan J. Bieber, Su-Youne Chang, Kevin E. Bennet, Kendall H. Lee, J. Luis Lujan
Department of Neurologic Surgery, Mayo Clinic

Seizure Suppression through Endopiriform Nucleus (EnPirNu) Stimulation in an In-Vivo Model
Vivek Nagaraj, Xiaofeng Yang, Keshab Parhi, Thomas Henry, Theoden Netoff
University of Minnesota, Minneapolis, MN

Deep Brain Stimulation of the Inferior Colliculus for Treating Tinnitus
Sarah J. Offutt, Alexander R. Konop, Hubert H. Lim
University of Minnesota, Minneapolis, MN

High Performance Electrode Material for Current and Future Implantable Neuromodulation Devices
Artin Petrossians, Jack Whalen, Florian Mansfeld, James Weiland
University of Southern California, Los Angeles, CA

An Intelligent Energy-Efficient Implantable CMOS Neurotrophic Factor Delivery Micro Neural Prosthetic to Promote Personalized Therapy for Neurological Disorders 
Mohammad Poustinchi, Sam Musallam
McGill University, Montreal, Canada
 
Fornix High Frequency Stimulation Induces BOLD Change and DA Release in Hippocampal and Mesolimbic Circuitry
Erika K. Ross, Hoon-Ki Min, Joo Pyung Kim,  Seong Rok Han, Kendall H. Lee
Mayo Clinic, Rochester, MN

Neurotransmitter-Based Stimulation of Retinal Ganglion Cells Offers Advantages Over Electrical Stimulation
Corey M. Rountree, Samsoon Inayat, Laxman Saggere, John B. Troy
Northwestern University, Evanston, IL

Utilizing Individual Endogenous Synchrony Dynamics in the Design of Electrical Deep Brain Stimulation Improves the Efficacy of Disrupting Temporal Lobe Seizures
Tiwalade Sobayo, David J. Mogul
Illinois Institute of Technology, Chicago, IL

Signal Processing Circuitry for Neuromodulation of the Vestibular System: A Comparison of Three Implementations
Hakan T&#243reyin, Pamela Bhatti
Georgia Institute of Technology, Atlanta, GA

Neurobiological Mechanisms of Deep Brain Stimulation in a Preclinical Model of Treatment Resistant Depression
Susannah J. Tye, YeSul Kim, Kathryn O’Connor, Ashlie Reker, Chunling Hu, Shari Sutor, Kendall H. Lee, Kevin E. Bennet, Mark A. Frye
Mayo Clinic, Rochester, MN

 

NONINVASIVE NEUROMODULATION

tDCS of Motor Cortex Modulates Motor Imagery Power
Bryan S. Baxter, Abhrajeet Roy, Bin He
University of Minnesota, Minneapolis, MN

6-Hz Primed vs. Unprimed Low-Frequency Repetitive Transcranial Magnetic Stimulation in Stroke
Jessica M. Cassidy, David C. Anderson, Mo Chen, William Thomas, James R. Carey
University of Minnesota, Minneapolis, MN

Pathophysiology of Spasmodic Dysphonia: A Combined TMS and fMRI Study
M. Chen, R. L. Schmidt, J. Camchong, B. A. Mueller, K. O. Lim, T. J. Kimberley
University of Minnesota, Minneapolis, MN

Spasmodic Dysphonia Brain Excitability Assessment Using Thyroarytenoid Muscle EMG Responses to TMS over Laryngeal Motor Cortex
M. Chen, R. L. Schmidt, T. J. Kimberley
University of Minnesota, Minneapolis, MN

Suppression of Subthalamic Nucleus Neurons by Magnetic Stimulation using Micro-coils
Shelley I. Fried, Seung Woo Lee
Harvard Medical School/MGH, Boston, MA

Enhancing Cognitive Control Using Transcranial Direct Current Stimulation (tDCS) and Concurrently Recorded EEG
Casey S. Gilmore, Carolyn L. Gentz, Brent G. Nelson, Molly Gierke, Kelvin O. Lim
Defense & Veterans Brain Injury Center, Minneapolis, MN

Synchronized Body and Acoustic Stimulation Induces Auditory Plasticity: Implications for a New Noninvasive Tinnitus Treatment
Cory D. Gloeckner, BenjaminT. Smith, Craig D. Markovitz, Hubert H. Lim
University of Minnesota, Minneapolis, MN

Enhanced Neuromodulatory Effect of Repetitive Transcranial Magnetic Stimulation with Novel Waveforms
Stefan M. Goetz, Bruce Luber, Sarah H. Lisanby, Cassie I. Kozyrkov, David L. Murphy, Warren M. Grill, and Angel V. Peterchev
Duke University, Durham, NC

A Novel Method to Induce Inhibition in Primary Motor Cortex by rTMS
L. Golob, M. Chen, R. L. Schmidt, T. J. Kimberley
University of Minnesota, Minneapolis, MN

Evaluation of Motor Network Interactions using Combined Transcranial Magnetic Stimulation and EEG
Nessa Johnson, Bin He
University of Minnesota, Minneapolis, MN  

Computational and Experimental Analysis of TMS-Induced Electric Field Vectors Relevant to Neuronal Activation
Todd D. Krieg,  Felipe S. Salinas, Peter T. Fox, David J. Mogul
Illinois Institute of Technology, Chicago, IL

Direct Measurement of the Response of PFC Pyramidal Neurons to Magnetic Stimulation
Seung Woo Lee, Shelley I. Fried
Harvard Medical School/MGH, Boston, MA

Investigating Paired Cortical And Acoustic Stimulation As A Treatment For Chronic Tinnitus
Craig D. Markovitz, Kyle A. Wesen, Patrick S. Hogan, and Hubert H. Lim
University of Minnesota, Minneapolis, MN

Development of Variable "Halo Coil" Configuration for Deep Brain Transcranial Magnetic Stimulation
Y. W. Meng, J. K. Qu, R. L. Hadimani, L. J. Crowther, D. C. Jiles
Iowa State University, Ames, IA

Increase in Gamma Power and Functional Connectivity Correlates with Clinical Response in Repetitive Transcranial Magnetic Stimulation (rTMS) for Depression
Yagna Pathak, Oludamilola Salami, Sylvain Baillet, Zhimin Li, Christopher R. Butson
Marquette University, Milwaukee, WI

Investigation in Pediatric Atereognosis Following 6-Hz Primed Low-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) and Constraint Induced Movement Therapy (CIMT)
Tonya L. Rich, Jessica M. Cassidy, Ann E. Van Heest, Linda E. Krach, James R. Carey, Bernadette T. Gillick
University of Minnesota, Minneapolis, MN

High Definition Transcranial Direct Current Stimulation Acutely Modulates Spontaneous Low Frequency Cortical Synchronization: Evidence from Simultaneous tDCS-EEG
Abhrajeet Roy, Bryan Baxter, Bin He
University of Minnesota, Minneapolis, MN

Optimizing Montages for Multifocal Transcranial Current Stimulation of Specific Targets: A Solution Based on Realistic Models of Electric Fields
G. Ruffini, M. D. Fox, O. Ripolles, P. C. Miranda, A. Pascual-Leone
Starlab Barcelona, Barcelona, Spain 

Effect of rTMS and Sensorimotor Retraining in Focal Dystonia
Rebekah L. Schmidt, Mo Chen, Catherin M. Buetefisch, Teresa J. Kimberley
University of Minnesota, Minneapolis, MN

Evaluation of the Therapeutic Effect of Theta Burst Stimulation in Schizophrenia: A Double-Blinded and Randomized Sham Controlled Resting-State EEG study
Guofa Shou,  Qian Guo, Chunbo Li, Kelvin Lim, Jijun Wang, Bin He, Lei Ding
University of Oklahoma, Oklahoma, OK
 
Transcranial Direct Current Stimulation for Obesity
Dennis Q. Truong, G. Magerowski, G. L. Blackburn, M. Alonso-Alonso, M. Bikson
City College of the City University of New York, New York, NY

 
IMAGING, MODELING AND BIOMARKERS FOR NEUROMODULATION

Information Theoretic Metrics as Biomarkers of Parkinson’s Disease Symptom Severity
Collin Anderson, Alan "Chuck" Dorval
University of Utah, Salt Lake City, UT

Identifying DBS Targets with fMRI and DTI at 7T MRI
Philip Burton, Yuval Duchin, Noam Harel
University of Minnesota, Minneapolis, MN

Patient-Specific Targeting with 7T MRI for DBS Applications
Yuval Duchin, Guillermo Sapiro, Kenneth Baker, Jon McIver, Jerrold Vitek, Noam Harel
University of Minnesota, Minneapolis, MN

Source Analysis Reveals Cortical Behavior During Motor Imagery Tasks
Brad Edelman, Bin He
University of Minnesota, Minneapolis, MN

Subject-Specific Computational Modeling to Predict Neural Activation During Transcranial Magnetic Stimulation
Brian D. Goodwin, Christopher R. Butson
Marquette University, Milwaukee, WI

Understanding the Emergence of Oscillatory Activity in a Computational Model of Parkinson’s Disease and Predicting Frequencies for Optimal Suppression Using Deep-Brain Stimulation
Abbey B. Holt, Theoden I. Netoff
University of Minnesota, Minneapolis, MN

White Matter Tracts in Deep Brain Stimulation: Using 7T MRI DTI Data to Define Potential Targets
Eleanor Orehek, Yuval Duchin, Jerrold Vitek, Noam Harel
University of Minnesota, Minneapolis, MN

3D Visualization of Colormap Data in the Auditory Midbrain
Luke T. Parker, Daniel Kastl, Cory Gloeckner, Sarah J. Offutt, Hubert H. Lim
University of Minnesota, Minneapolis, MN

Volumetric Analysis of Basal Ganglia Structures in 7T MRI of Patients with Movement Disorders
Edgar Pena, Yuval Duchin, Noam Harel
University of Minnesota, Minneapolis, MN

Optimizing the Design and Use of Radially Segmented Deep Brain Stimulation Leads Using Computational Modeling
Benjamin A. Teplitzky, Joe Xiao, Laura M. Zitella, Matthew D. Johnson
University of Minnesota, Minneapolis, MN

In-Vivo Visualization of Thalamic Nuclei Using 7T Susceptibility-Weighted MRI for Localizing DBS Targets
Joe Xiao, Laura Zitella, Daniel Kastl, Yuval Duchin, Essa Yacoub, Noam Harel, Matthew D. Johnson
University of Minnesota, Minneapolis, MN

Structural 7T MRI Tools: Visualizing the Brainstem for Deep Brain Stimulation Targeting
Laura M. Zitella, Joe Xiao, Ben Teplitzky, Daniel Kastl, Yuval Duchin, Essa Yacoub, Noam Harel, Matthew D. Johnson
University of Minnesota, Minneapolis, MN

Neural Correlates of Sustained Pain Induced by Thermal Stimulation
Clara Huishi Zhang, Yunfeng Lu, Bin He 
University of Minnesota, Minneapolis, MN

Regular Oscillations in LFP Power During Timing in Macaque DLPFC
Simeng Zhang, Patrick K. Fahey, Stephen Kerrigan, James Ashe
University of Minnesota, Minneapolis, MN


 



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